Have refined my list down to a tee over the years, this is a fairly minimalistic setup but works brilliantly well for me.
Tools
The KTM has a fantastic tool kit, so apart from a Leatherman, tube changing goodies and some cable ties I take nothing extra. Oh ya have only had good results with my slime compressor.
Clothes
The amount of clothes I take is always the same, whether I go away for 4 days or 14 days.
First Ascent technical / utility pants (legs zip off so they do double duty as swimming trunks and something for at night. Presentable enough to go to a restaurant with)
Adidas Soft shell top (packs small, black does not show dirt, also presentable for nice restaurant dinner)
2 x MX type riding shirts (The one I wear will get washed at night, also nice extra layer if cold at night)
2 x T-shirts (same story, wash and wear)
2 x Riding socks (pair I wear will get washed at night)
3 x underwear (wash whenever I shower)
Sneakers (do not like wearing plakkies in the bush and I don't wear crocs)
Hat
Camping
2 man bicycle tent from Midas (do not like bivvies as I prefer to have my kit with me in the tent. Straps to the back of my Giant Loop)
First Ascent Adventure Light Sleeping bag (cannot rave enough about this one, one of my best purchases ever. You have to see this thing to believe how small it packs and how light it is)
ATG Stretcher (Another awesome piece of kit, sleeping on a bike trip used to be a big problem for me, no more, get an easy 8 hours of proper sleep per night in, it's so comfortable)
Inflatable cushion (R30 from Due South, weighs nothing, more comfortable than sleeping on a bag full of clothes)
Spork (use my Leatherman for a knife)
Cup - packs of instant coffee / sugar / milk packs in here as well
K-Way Microfiber towel (compact & lightweight but dries you off well enough)
"Varkpan" (serves as kettle, pot and plate)
Kovea burner and gas (works well enough but carting around gas is a schlep, will change to something that can use petrol. Perhaps the ATG stove)
Small bottle of shower gel, small toothpaste and deodorant
Toilet Paper
Gadgets
GoPro 3
Garmin eTrex 20 (This thing is the business. No mucking around with power connections, this one gets about 24 hours on 2 x AA batteries. Very visible in direct sunlight plus none of that touchscreen rubbish which never works with a glove. It has a joystick that is easy to manipulate while riding. I use the Garmin bicycle mount to mount it to my handlebars)
Ledlenser SEO7R headlamp - the best headlamp available, taking into account power, size and cost.
Spare pack of AA & AAA batteries (for Headlamp and GPS).
Spare battery and memory card for the Gopro
Battery pack (has USB connections so I use it to charge my phone and GoPro at night)
Hella -> Usb \9Use it to charge above battery pack while I ride)
Food
I don't bother, unless we're rough camping somewhere in the sticks. Rather have a big breakfast that stick on the ribs till the afternoon and then get something at the last shop I pass before we hit the campsite. Not a picky eater so happy with something as simple as a tin of bully beef. That said, as a rule I'll have a pack of tuna, pack of biltong and one or two energy bars in the tankbag for emergencies, energy bars also make nice gifts.
Water is the one thing I don't play with - I'll take 2 x 1L water in the Giant Loop, 2L in my camelback and 2 x 500ml in my tankbag, as a minimum. Not a fan of energy drinks, rather eat properly, also it's difficult to wash hands / face / visor / wound with a sticky energy drink.
First Aid Kit
Don't know First-Aid unfortunately, so my FA kit is fairly basic
Imodium
USN Cramp Block
Assorted Plasters
Rehidrat
Mercurochrome
Savlon
Grandpa Powders
Bandage, Cotton Wool
Rennies
Weight Distribution
Two basic principles to adhere to, keep the weight down low and keep it in front of the rear axle.
Tools go into a GL pod bag and into the right "leg" of the Giant Loop
Stretcher, towel, sleeping back goes in the left "leg"
Clothes are rolled (not folded) and go into a compression bag in the GL.
Have a spare compression bag for dirty / wet clothes
First Aid Kit and oven goes into the center compartment of the GL so it's always easily accessible
Tent straps to the back of the Giant Loop
I have the SW-Motech Enduro Large tankbag, quality is very good but it's a bit large. When I stand I can feel it against my crotch so will swap for something smaller one day (the bag, not my crotch). Perhaps a smaller KTM one, they seem rather nice + you can carry them as a back pack. Anyway, all my random stuff goes in there (hat, phone, drink, snack, whatever).